Diablo 3 is a deep dive into Tyrael's tale, as he becomes Tyrael D2R Items the Fallen Star by tearing off his wings and crashing into Sanctuary in which the descendents of Nephalem dwell. When he joins with one of these powerful descendant, Tyrael defeats the primary evils and takes responsibility for the Black Soulstone. After the Archangel of Death, Maltheal, went after the stone and began to attack his followers It was Tyrael who was the one to send his friend into Pandemonium to destroy death itself.
Tyrael chooses to keep his mortal form . He then reunites with his angelic brethren to become both the Aspect of Justice and of Wisdom. Diablo 3 ends with him contemplating whether his new mortal companion, who is likely to be corrupted, will one day become the next danger in Heaven, Hell, and Sanctuary as well as the life itself. In the end, The Aspect of Justice and Wisdom most likely won't be content while Inarius marches an army upon Hell in search of his former love, Lilith.
The latest Diablo 4 cinematic trailer from Blizzard showcases Inarius confronting Lilith and armies on both of their backs. Although the film doesn't show Tyrael's involvement directly, his development of Horadrim and influence with the various Paladins of Sanctuary suggests that he's at work. Light and dark clash across the field, and now-mortal Tyrael is a middleman.
It is highly likely that his presence will be felt through these intermediaries until events take his hands. Tyrael still feels the repercussions of destroying his Worldstone at the conclusion of Diablo 2. This mystical object protected Sanctuary from Heaven and Hell and now acts as a protector for the area in its place. Tyrael does not appear likely to lead any further adventures into Hell or travel any further that The Pandemonium Fortress, where he might offer advice similar to Deckard Cain to buy diablo 2 resurrected items those who stay and listen.